We see many, many cats like this who just do not like to be seen by the veterinarian. I agree with you that a total physical is very important so I applaud you for trying to get this done. Unfortunately, sedatives at home can be tricky - first getting it into her and then also if she is upset she may override the effects.
If the trouble is physically getting there, you can do a couple things. Place her carrier out a week or two before the visit. Throw her toys in there, give her treats or feed her in there so she is used to going in and out of it. It often helps to use a larger carrier rather than a smaller one. If this does not work and you have to assist Kati into her carrier - try to isolate her to a small area with no hiding places (like a bathroom) an hour or so before you leave. I often suggest that you use a large towel to cuddle her and cover her head as you put her in the carrier. Do this carefully (be extremely careful you do not get bit) and calmly (she will pick up on your stress). It may be easier to back her into the carrier or turn it up on its end and lower her rear in. You could also consider a top-loading carrier. This all requires a little tough love...remember 5 or 10 minutes of trauma in the context of her entire life is not that much.
A couple suggestions regarding the veterinarian. For cats that have some anxiousness with going to the vet...it often helps to have an early morning appointment or one right after lunch. This minimizes the chance you may have a long wait that could stress Kati out. I also suggest you find a veterinarian who has experience dealing with temperamental cats. Many veterinarians are intimidated by a cat that acts out. Cat only practices are often a good option, as they deal with only cats and see many strong feline personalities (don't forget I am biased on this issue since I have always worked in cat-only clinics).
I hope this information helps. In many cases, the stress you feel surrounding the visit is more than Kati likely feels. But because it is so important, keep trying!
Source: http://www.catchow.com
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